![Treatment-resistant depression affects at least 30% of patients.](https://imagenes.elpais.com/resizer/v2/DLI6HMEG2NGPBNSP4YZXWGEPAE.jpg?auth=6f59080b21a53b3bda2c54806d73e51519f0ba94633400208e381693291ad8fb&width=414&height=233&smart=true)
What to do if depression isn’t responding to treatment?
It’s key to make sure past diagnoses were correct, evaluate past attempts and get to know different evidence-based treatments. An integrated approach is fundamental, rather than one based exclusively on pharmaceuticals